Dopaminergic Treatment in Idiopathic Restless Legs Syndrome

Treatment Options for Idiopathic Restless Legs Syndrome

The emergence of new effective therapies for idiopathic restless legs syndrome (iRLS) or Willis–Ekbom disease (WED) during the last 15 years resulted in an exponential increase of reports regarding this syndrome and, especially, treatment options. In this review, we summarise the main findings related to neuropharmacological aspects and non-pharmacological therapies of idiopathic RLS (iRLS). As...

Dopaminergic treatment in idiopathic restless legs syndrome: effects on subjective sleepiness.

OBJECTIVES To assess frequency and characteristics of excessive daytime sleepiness (EDS) in restless legs syndrome (RLS) and the evolution of EDS under different RLS therapies. METHODS We analyzed data from the "Swiss RLS" study, which was conducted to compare treatment efficacy and safety of the dopamine agonist pramipexole (PPX) versus L-dopa/benserazide (L/B) in de novo patients with idiop...

Restless Legs Syndrome Prevalence in Major Thalasemia Tabriz Children Hospital

Restless Legs Syndrome: Diagnosis, Treatment and Pathophysiology

............................................................................................................... .12 Introduction.............................................................................................................12 Methods............................................................................................................. ....13 Subjects............................

Apomorphine in idiopathic restless legs syndrome: an exploratory study.

BACKGROUND Dopaminergic and opioidergic drugs have been found to be effective in patients with restless legs syndrome (RLS). OBJECTIVES To test the effect of apomorphine--a combined opioidergic and dopaminergic agonist--and subsequent selective antagonism by naloxone and metoclopramide on subjective and objective symptoms in patients with idiopathic RLS. METHODS Nine patients with RLS were ...